Tetrapeptide-30 Injection

(1) Age related age spots and fading of yellowish brown complexion

As age increases, the metabolic capacity of the skin gradually decreases, and the rate of melanin metabolism excretion slows down. At the same time, long-term accumulated light damage can disrupt the color regulation mechanism in the skin, ultimately forming age spots with irregular boundaries and uneven color depth. At the same time, the overall complexion presents an unhealthy yellow brown color, commonly known as "yellowing". The difficulty of improving this type of pigmetation problem is much higher than ordinary tanning, as it not only involves excessive melanin production, but also multiple problems such as decreased derma metabolic capacity and deeper pigmetation deposition.

A study on intervention for age spots showed that after continuous use of formulations containing it for 8 weeks, significant fading effects were observed in both the volume and color depth of age spots in subjects.

The core reason for this result is that long-term use can continuously regulate the overall level of tyrosinase in the derma, allowing the already disordered melanin production rate to return to normal physiological levels. At the same time, its anti-inflammatory effect can improve the chronic low-grade inflammation that exists around age spots for a long time. This type of chronic inflammation is an important hidden factor that leads to the continuous deepening and difficulty in fading age spots.

In practical application scenarios, it is often added to anti-aging and skin brightening night cream and essence products. For people over 30 years old with color problems in early aging, this kind of product does not need to establish tolerance, and long-term use will not bring additional burden to the derma. It can gradually improve the complexion and age spots problems caused by aging while anti-aging, and realize the dual role of "skin brightening+anti-aging".

(2) Post inflammatory pigmentation (PIH) and acne scar repair

Post inflammatory pigmetation is a highly prevalent type of pigmetation problem in Asian populations, which can be triggered by acne, derma barrier damage, medical treatment, trauma, and other factors. Many people may leave dark acne scars after acne subsides, or experience anti blackening after beauty treatments such as acid brushing and photon rejuvenation. The core cause of these pigmetation problems is the excessive release of local inflammatory factors in the derma, which stimulates abnormal activation of melanocytes.

Traditional whitening ingredients often face a dilemma in improving pigmetation after inflammation: if the ingredients are highly irritating, they can further exacerbate skin inflammation and make pigmetation problems more severe; If the ingredients are too mild and it is difficult to achieve effective whitening effects. And its characteristics perfectly adapt to this scenario.

It can directly block the induction of melanin production by inflammatory factors by inhibiting the expression of POMC, and can also directly reduce the levels of inflammatory factors such as IL-6 and IL-8, thereby fundamentally reducing the local inflammatory response of the derma. Relevant clinical test data shows that adding 0.01% tetrapeptide-30 injection in combination with VC phosphate sodium cream, used twice a day, can significantly reduce the marks left by acne after 12 weeks.

In practical application, it is widely added to the acne repair essence and medical art post repair merchandise. This kind of merchandise will not stimulate the damaged derma that is already in the inflammatory state, but also achieve the effect of relieving inflammation, preventing and reducing acne marks at the same time. It is especially suitable for people who are prone to post inflammation pigmetation such as sensitive muscles and oily acne muscles for long-term use. It can also be used as a special skin care ingredient for anti black prevention after medical art, significantly reducing the anti black risk after the photoelectric project.

(3) Intervention of pregnancy spots and hormone related pigmentation problems

Pregnancy spots, also known as melasma, are a type of pigmetation problem that is highly related to fluctuations in hormone levels in the body. They are common in pregnant women and can also occur in people who take hormone drugs for a long time and have endocrine disorders. The pathogenesis of this type of pigmetation problem is more complex than ordinary pigmetation, involving not only melanocyte activation, but also multiple problems such as chronic inflammation and vascular dilation in the derma. The intervention effect of conventional whitening ingredients is often very limited and prone to recurrence.

According to relevant clinical application data, adding 0.01% of its cream in combination with phenethyl resorcinol and applying it twice a day to the area of pregnancy spots, a significant reduction in pregnancy spots can be observed after 15 days.

The achievement of this effect relies on its ability to regulate multiple pathways: it can not only inhibit the overexpression of alpha MSH induced by hormone fluctuations, block the excessive stimulation of melanocytes by hormone signals, but also improve the chronic inflammatory state that exists in the lesions of melasma for a long time, breaking the vicious cycle of "hormone fluctuations inflammation pigmetation".

In practical application, it is often used in mild spot lightening essence merchandise. For people who cannot use powerful whitening ingredients during pregnancy and lactation, and for daily maintenance of difficult color problems such as chloasma, its low irritation and high safety enable these special people to gradually improve their color problems without irritating the derma, avoiding the risk of derma barrier damage caused by traditional powerful spot lightening ingredients.

(1) The core functional ingredients of basic brightening skincare products

Skin brightening cream and skin brightening essence are the most basic application carriers of tetrapeptide-30 injection. This kind of product is intended for ordinary consumers with daily whitening needs. It does not need a special threshold for use and is suitable for long-term use by people with all derma types. Due to its suitability for various complexions, there is no problem of some whitening ingredients having poor effects or even inducing darkening in darker complexions. Therefore, it can be adapted to a wide range of consumer groups in different regions and complexions.

Many derma brightening merchandise that focus on "mild whitening" and "early C, late A pairing" choose to compound Tetrapeptide-30 with vitamin C derivatives. Relevant studies have confirmed that when used in combination with sodium ascorbate phosphate (a stable VC derivative), the whitening and brightening performance can be significantly improved, achieving a synergistic effect of "upstream signal blockade+downstream melanin reduction", which is several times more effective than using VC derivatives alone. This compound formula not only retains the reducing and whitening advantages of VC, but also solves the problems of single action pathway, easy deactivation, and intolerance of some people caused by ordinary VC derivatives, thus improving the mildness and effectiveness of the product at the same time.

(2) Active ingredients added to makeup products with whitening effects

Traditional whitening and makeup merchandise mostly rely solely on physical coverage to achieve instant complexion brightening, and cannot truly improve the skin's color problems during the makeup process. Even the powdery components in many makeup merchandise can burden the derma, and long-term use can easily induce darkening of the derma. Its high stability and hydrophilicity enable it to be added to the cosmetics merchandise such as brightening foundation make-up, powder, brightening isolation, etc., so that the cosmetics merchandise have the additional effect of "skin care and brightening while making up" without affecting the nature of the powder and damaging the makeup effect.

When consumers use this kind of brightening foundation make-up added with tetrapeptide 30 in daily use.

They can let the active ingredients slowly penetrate into the derma within a few hours of makeup without additional skin care steps, and continue to play the role of color regulation. After long-term use, even if the foundation make-up is removed, they can observe that their derma color becomes more uniform and transparent, and get rid of the pain point of traditional makeup that "the more foundation make-up is used, the darker the derma". This type of product is particularly suitable for the workplace population who wear makeup for a long time. While meeting their daily makeup needs, it also achieves the integration of makeup and skincare functions.

(3) Customized use of whitening products in special scenarios

In addition to conventional brightening and makeup merchandise, more customized color regulation applications can also be developed based on different segmentation scenarios.

For example, when added to sunscreen merchandise, tetrapeptide-30 injection can further intervene in the melanin generation signal induced by ultraviolet rays that have already entered the derma on the basis of physical and chemical sunscreen blocking ultraviolet rays, achieving a dual light protection of "external blocking+internal blocking" and greatly improving the anti tanning ability of sunscreen merchandise; Adding it to hand cream and body lotion can improve the local dullness of complexion and pigmetation in joints caused by long-term exposure of body parts such as arms and legs to ultraviolet radiation, achieving uniform brightening of the entire body's complexion; Added to men's specific brightening merchandise, its fragrance free and low irritation properties also meet the demand for refreshing and burden free skincare merchandise for men, helping to improve the common problems of dark and yellow derma caused by excessive oil secretion and inflammation in men's derma.