Decapeptide-12 Injection

Decapeptide-12 Injection
Details:
1.General Specification(in stock)
(1)API(Pure powder)
(2)Injection
(3)Cream
2.Customization:
We will negotiate individually, OEM/ODM, No brand, for secience researching only.
Internal Code: KP-1-19/003
Decapeptide-12 CAS 137665-91-9
Molecular formula: C65H90N18O17
HS code: N/A
Molecular weight: 1395.52
Manufacturer: BLOOM TECH Wuxi Factory
Analysis: HPLC, LC-MS, HNMR
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Technology support: R&D Dept.-4
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Description
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As an emerging sub component of the active peptide hair care track in recent years, decapeptide-12 injection, with its precise signal regulation ability, breaks free from the limitations of traditional haircare ingredients that only act on the surface of hair, achieving full coverage from scalp microenvironment regulation, hair follicle vitality activation to hair structure strengthening. Unlike the well-known acetyltetrapeptide-3, it is more inclined to provide targeted intervention for scalp aging hair problems, especially suitable for non pathological hair aging problems caused by long-term staying up late, photoaging, and environmental pressure in contemporary people.

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decapeptide-12 | Shaanxi BLOOM Tech Co., Ltd

decapeptide-12 injection | Shaanxi BLOOM Tech Co., Ltd

decapeptide-12 cream | Shaanxi BLOOM Tech Co., Ltd

Decapeptide-12 Price List | Shaanxi BLOOM Tech Co., Ltd

Decapeptide-12 Price List | Shaanxi BLOOM Tech Co., Ltd

Method of Analysis

Decapeptide-12 COA

 
Shaanxi BLOOM Tech Co., Ltd
Certificate of Analysis
Compound name Decapeptide-12
Grade Pharmaceutical grade
CAS No. 928007-64-1
Quantity 70g
Packaging standard PE bag+Al foil bag
Manufacturer Shaanxi BLOOM TECH Co., Ltd
Lot No. 202601090056
MFG Jan 9th 2026
EXP Jan 8th 2029
Structure

decapeptide-12 structure | Shaanxi BLOOM Tech Co., Ltd

Item Enterprise standard Analysis result
Appearance White or almost white powder Conformed
Water content ≤5.0% 0.37%
Loss on drying ≤1.0% 0.75%
Heavy Metals Pb≤0.5ppm N.D.
As≤0.5ppm N.D.
Hg≤0.5ppm N.D.
Cd≤0.5ppm N.D.
Purity (HPLC) ≥99.0% 99.90%
Single impurity <0.8% 0.65%
Total microbial count ≤750cfu/g 80
E. Coli ≤2MPN/g N.D.
Salmonella N.D. N.D.
Ethanol (by GC) ≤5000ppm 500ppm
Storage

-20°C, protect from light

decapeptide-12 NMR | Shaanxi BLOOM Tech Co., Ltd

Shaanxi BLOOM Tech Co., Ltd

Chemical Formula C65H90N18O17
Exact Mass 1395
Molecular Weight 1396
m/z 1395 (100.0%), 1396 (70.3%), 1397 (24.3%), 1396 (6.6%), 1398 (4.7%), 1397 (4.4%), 1397 (3.5%), 1398 (2.5%), 1398 (1.6%), 1396 (1.0%)
Elemental Analysis C, 55.94; H, 6.50; N, 18.07; O, 19.49

Applications

 

Unlike the strong irritant properties of medicinal ingredients such as minoxidil, decapeptide-12 injection acts as a mild signal peptide that regulates the growth signal of folliculitis cells, without causing side effects such as epicranium irritation or excessive alopecia. It has gradually been applied in high-end scalp anti-aging, anti alopecia and hair repair scenarios, providing a new solution for pain points such as "scalp aging alopecia" and "premature hair aging" that traditional haircare products cannot solve.

decapeptide-12 uses | Shaanxi BLOOM Tech Co., Ltd

The core use of scalp anti-aging and hair follicle vitality activation

The aging rate of the epicranium in contemporary people is far exceeding expectations. Clinical data from the haircare industry shows that the aging rate of the epicranium after the age of 25 is twice that of facial skin. Long term exposure to ultraviolet radiation, oxidative stress, and staying up late can cause the accumulation of inflammatory factors, leading to the gradual loss of collagen protein in the dermis layer of the epicranium, loss of support and displacement of folliculitis. The growth cycle of folliculitis is shortened, and originally healthy hair gradually becomes thinner and softer, eventually entering the resting period ahead of schedule. This is also the core reason why many young people, even though they do not have genetic alopecia, experience widened hairlines and sparse epicranium early on.

The core role in such scenarios is to act as a signal peptide targeting the dermal papilla cells of the epicranium, promoting the synthesis of type I and III collagen in the epicranium dermis, and building a more stable supportive microenvironment for folliculitis, fundamentally improving the problem of decreased folliculitis vitality caused by epicranium relaxation. In the application scenario of high-end epicranium anti-aging essence, 0.005% concentration of it can penetrate into the dermis of the epicranium, regulate the cell signal pathway around the folliculitis, inhibit the matrix metalloproteinase activity that will damage the supporting structure of the folliculitis, and avoid the excessive decomposition of epicranium collagen. The clinical tracking data of 2025 of a third-party haircare laboratory in China showed that after 12 weeks of continuous use of the epicranium anti-aging essence, the elasticity of the epicranium of the subjects increased by 31%, and the density of the supporting structures around the folliculitis increased significantly.

decapeptide-12 signal | Shaanxi BLOOM Tech Co., Ltd
decapeptide-12 hair | Shaanxi BLOOM Tech Co., Ltd

The folliculitis originally displaced due to epicranium relaxation returned to the upright and healthy state, and the growth cycle of the hair was extended by an average of 42%. Many of the velveteen hairs that could only grow to 3cm before they fell off in advance gradually became thicker and longer into healthy final hair, which directly improved the problem of widened hair seams on the top of the head visually. Unlike traditional anti shedding ingredients, it does not rely onthe logic of dilating epicranium blood vessels to function, and there is no problem of diminishing effectiveness of caffeine based ingredients after long-term use. It also completely eliminates the side effects of hirsutism and epicranium redness that may be caused by minoxidil based ingredients. Even sensitive epicranium individuals can use it daily for a long time. In the subdivision scenario of epicranium photoaging protection, the epicranium is the most vulnerable part of the human body to direct ultraviolet radiation. Long term ultraviolet radiation will generate a large amount of free radicals on the epicranium, accelerate the breakdown of epicranium collagen, and cause premature aging of folliculitis.

Many people experience thinning and easy breakage of hair at the hairline by the age of 30, which is essentially due to the long-term exposure of the epicranium in the hairline area to direct ultraviolet radiation, resulting in severe photoaging damage. Decapeptide-12 injection can regulate oxidative stress signals inside the epicranium, reduce the number of pro-inflammatory factors generated by the epicranium after UV irradiation, and reduce the damage of free radicals to folliculitis DNA. It is equivalent to building an invisible "anti photoaging protective film" inside the epicranium. Many high-end haircare products focusing on sunscreen of epicranium are added to the epicranium protection essence. Applying it on the epicranium before outdoor activities for a long time can significantly reduce the aging damage of ultraviolet rays on the epicranium, avoid the problems of premature aging of the epicranium and backward movement of the hairline for people who work outdoors for a long time, and perfectly match the epicranium anti-aging needs of outdoor workers and long-term outdoor sports people.

decapeptide-12 hairline | Shaanxi BLOOM Tech Co., Ltd
decapeptide-12 application | Shaanxi BLOOM Tech Co., Ltd

In the scenario of repairing epicranium aging caused by staying up late, contemporary young people who stay up late for a long time can release a large amount of inflammatory cytokine IL-6 from the epicranium, continuously damaging the healthy microenvironment of folliculitis. Many people will find a significant increase in alopecia the next day after staying up late, and long-term staying up late will quickly lead to hair thinning problems.

It can gently regulate the latent inflammation of the epicranium caused by staying up late, avoid the continuous interference of inflammatory factors with the normal growth cycle of folliculitis, help the epicranium quickly recover to a stable state after staying up late, and reduce abnormal alopecia caused by staying up late. This is also the core reason why many young haircare products that focus on "staying up late to prevent alopecia" choose it as the core ingredient. It perfectly adapts to the haircare habits of young people, and does not need to change the lifestyle rhythm of staying up late, which can reduce the damage of bad habits to hair from the epicranium level.

The use of non male alopecia and reduction of abnormal alopecia

In addition to alopecia caused by epicranium aging, the high proportion of stress type resting period alopecia and postpartum alopecia in contemporary urban populations belong to non androgen dependent alopecia types. The folliculitis of this type of alopecia population do not show pathological atrophy themselves, but due to internal hormonal fluctuations and pressure signal interference, a large number of folliculitis enter the resting period synchronously, causing a rapid increase in alopecia in a short period of time. Traditional strong anti shedding ingredients can easily bring additional stimulation to sensitive epicranium, and their high temperature and sex perfectly meet the hair fixing needs of this population. In the repair scenario of stress-induced resting period alopecia, many people may experience a daily loss of more than 100 strands of hair for several months after experiencing long-term high-pressure work and significant emotional fluctuations.

decapeptide-12 male | Shaanxi BLOOM Tech Co., Ltd
decapeptide-12 shampoo | Shaanxi BLOOM Tech Co., Ltd

Ordinary anti shedding shampoo is difficult to quickly improve this abnormal alopecia state. Tenpeptide-12 can regulate the growth cycle signal of folliculitis, allowing a large number of folliculitis that have entered the resting period early to smoothly return to the growth period, breaking the vicious cycle of "synchronous resting of a large number of folliculitis → concentrated alopecia". According to the clinical tracking data of a domestic medical beauty haircare center, 86 subjects with stress type alopecia during the rest period used the fixed hair essence for 8 weeks continuously, 91% of the people's daily average alopecia decreased from more than 120 to less than 50, and the hair roots of alopecia changed from the original dry and shriveled rest period to the full growth period. The whole process did not appear any uncomfortable reaction of redness and itching of the epicranium, which was far better than the traditional experience of strong stimulation anti alopecia ingredients. In the special scenario of postpartum alopecia, women may experience a significant increase in alopecia 3-6 months after delivery due to the rapid decline of estrogen in the body, causing a large number of folliculitis to enter a dormant period.

At this stage, women's epicranium is relatively sensitive and in a special physiological stage, making it completely unsuitable to use medicinal anti alopecia ingredients such as minoxidil to avoid unnecessary metabolic risks caused by the absorption of ingredients into the body through the epicranium. As a small molecule active peptide, it has extremely high biological safety and does not enter the human body's circulatory and metabolic system. It only works locally on the epicranium and can gently regulate the folliculitis cycle of the postpartum epicranium, helping the epicranium smoothly pass through the hormone fluctuation period and significantly reducing the duration of postpartum alopecia. Many haircare brands that specialize in postpartum care use it as their core hair fixing ingredient, which not only solves postpartum women's alopecia anxiety, but also completely avoids the safety risks of medicinal ingredients, becoming the preferred hair fixing product for many postpartum mothers.

decapeptide-12 anti | Shaanxi BLOOM Tech Co., Ltd
decapeptide-12 agent | Shaanxi BLOOM Tech Co., Ltd

In the repair scenario of alopecia after perming, for those who frequently perming, the alkaline components and oxidants in the perming agent can stimulate the epicranium, damage the healthy microenvironment around the folliculitis, and cause the folliculitis to enter the resting period prematurely, resulting in a significant increase in alopecia 1-2 months after perming. Many people's hair becomes increasingly sparse after frequent perming, which is essentially due to chemical stimulation damage to the folliculitis. It can alleviate the hidden inflammation of the epicranium caused by the residue of scalding agent, repair the microenvironment around the folliculitis damaged by chemical substances, and prevent the folliculitis from entering the rest period in advance due to chemical stimulation. Many high-end barber shops will add decapeptide-12 injection epicranium essence to the matching epicranium care project after scalding, and apply it directly on the epicranium after scalding, which not only alleviates the burning sensation of the epicranium after scalding, but also avoids the problem of alopecia after scalding from the root, so that people who frequently scald can maintain stable hair density.

References

1. Runhui Biotechnology (Weihai) Co., Ltd Technical Parameters Manual for Decapeptide-12 Cosmetic Raw Materials [R]. Weihai: Runhui Biotechnology (Weihai) Co., Ltd., 2024
2. Domestic third-party Haircare efficacy evaluation laboratory 2025 Clinical Tracking Report on Active Peptide Haircare Ingredients in Humans [R]. Guangzhou: Beauty Efficacy Evaluation Research Center, 2025
3. High end functional Haircare brand joint research and development center White Paper on Formula Technology for Scalp Anti Aging Products [R]. Shanghai: China Beauty Industry R&D Innovation Alliance, 2024
4. China Flavor essence and Cosmetic Industry Association Technical Specifications for the Safety of Cosmetic Raw Materials (2022) [S]. Beijing: China essence and Cosmetic Industry Association, 2022
5. Zhongfu Oil (Guangzhou) Group Co., Ltd Application Guide for High end Haircare Active Ingredients [R]. Guangzhou: Zhongfu Oil (Guangzhou) Group Co., Ltd

FAQ
 

What is the use of Decapeptide-12?

It reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation.

 

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