Acetyl Hexapeptide-3

1. Anti-Wrinkle Serums & Concentrates (Core Ingredient for Premium Functional Lines)

As a key anti-aging active ingredient for high-end functional skincare lines, acetyl hexapeptide-3 serves as a primary additive in anti-wrinkle serums and concentrates due to its botulinum toxin-like non-invasive anti-wrinkle mechanism. This ingredient has outstanding stability, adapting to the conventional pH range and processing temperatures of skincare products, and blends well with multiple active components. In premium anti-wrinkle serums and concentrates, its typical addition dosage ranges from 3% to 8%, while customized high-concentration concentrates can reach 10%. It is often compounded with hyaluronic acid, vitamin E, ergothioneine and other ingredients to create a multi-functional skincare system for anti-wrinkle, antioxidant and moisturizing effects.

Clinical skincare tests demonstrate that continuous use for 28 days can remarkably reduce the depth of facial expression lines, with prominent improvements on forehead lines, glabellar lines and superficial nasolabial folds. It works gently and delivers long-lasting effects. As an iconic ingredient in high-end anti-aging serum lines of international renowned brands, it meets the anti-wrinkle demands of young aging and mature skin of all types.

2. Anti-Wrinkle Eye Creams

The skin around the eyes is merely one-third the thickness of facial skin, with sparse sebaceous glands and sweat glands. It has weak water retention, is delicate and sensitive, and is the first area prone to wrinkles - also a prime application scenario for it.

With a small molecular size and excellent transdermal absorption capacity, this ingredient precisely acts on the orbicularis oculi muscle around the eyes, relieving excessive muscle contraction and effectively improving dynamic wrinkles such as crow's feet. Meanwhile, it inhibits the activity of matrix metalloproteinases, slows down the degradation of collagen and elastin in the dermis, and promotes collagen repair and regeneration, so as to fade static lines including dry lines and fine lines around the eyes, delivering dual effects of anti-wrinkle, firming and hydration.

Some high-end eye creams adopt microencapsulation technology to encapsulate it, which extends the ingredient's working duration and further lowers irritation, enabling long-term use on delicate periocular skin. It is a core additive in luxury anti-wrinkle eye creams.

3. Anti-Wrinkle Creams, Lotions & Neck Creams

Anti-wrinkle creams, lotions and neck creams represent the most widely used formulations of it, catering to daily anti-aging and firming care for the full face and neck, and meeting the anti-aging needs of general mature skin.

Lightweight and hydrating, lotions are suitable for oily skin, combination skin and use in spring and summer. The addition concentration is controlled between 2% and 5%, balancing a refreshing skin feel and mild anti-wrinkle effects without causing greasiness or breakouts.

Targeting horizontal neck lines and sagging neck skin, neck creams adopt a medium-to-high dosage of 5% to 8%. Combined with massage, the ingredient acts accurately on neck muscles and the dermis, improving neck lines caused by prolonged head lowering, muscle traction and collagen loss, and tightening the neck contour. It is an essential ingredient for comprehensive anti-aging care of the whole body.

4. Facial Masks (Sheet Masks, Wash-Off Gel Masks & Sleeping Masks)

As intensive skincare carriers, facial masks create an occlusive penetration environment to amplify the anti-wrinkle efficacy of it, suitable for periodic emergency anti-aging care and daily maintenance. Different mask types fit diverse skincare needs.

Sheet masks focus on instant repair and line reduction, with the ingredient content in essence ranging from 1% to 3%. Blended with moisturizers like hyaluronic acid and beta-glucan, the mask is applied for 15 to 20 minutes. Under occlusive conditions, the active ingredient penetrates rapidly to relieve dryness and instantly fade dry fine lines and temporary expression lines, ideal for skin emergency care after staying up late or sun exposure.Wash-off gel masks have a cool gel texture with an ingredient concentration of 3% to 5%.

Their low temperature soothes redness and heat on the skin. A thick layer locks moisture for a long time and continuously releases active substances to repair damaged skin and fade dry lines, perfect for sensitive skin and fatigued skin after staying up late.

Sleeping masks adopt a sustained-release formula with an addition level of 2% to 4%. Applied before sleep, they adhere to the skin for hours, acting continuously on facial muscles and the dermis to deliver anti-wrinkle, repair and moisturizing effects overnight. The skin feels visibly firmer and smoother in the morning, realizing non-invasive overnight anti-aging.

5. Post-Medical Aesthetic Repair Products

After aesthetic treatments such as photorejuvenation, fractional laser and microneedling, the skin barrier is impaired with weakened resistance, often accompanied by redness, stinging, dryness and deepened fine lines.Thanks to its low irritation, high activity and dual effects of repair and anti-aging, acetyl hexapeptide-3 becomes a core ingredient for dedicated post-procedure repair products.It effectively inhibits the release of inflammatory factors including TNF-α and IL-6, relieving post-treatment discomfort such as redness, stinging and burning sensations and mitigating skin inflammation. It also accelerates skin barrier repair and healing of damaged stratum corneum, reducing dryness and peeling after procedures.

Unlike ordinary repairing ingredients, it relaxes facial muscles simultaneously to prevent aggravated wrinkles caused by frequent facial movements after treatment, promotes collagen regeneration, consolidates the anti-aging results of aesthetic treatments, and lowers the risks of post-procedure sequelae such as pigmentation rebound and skin sagging.

In post-procedure repair serums and creams, the dosage of it is 2% to 5%. Formulas follow a minimalist and safe principle with no fragrances, alcohol or preservatives. The products can be used 3 to 7 days after treatment once the skin barrier is initially recovered, suitable for skin repair after various minimally invasive and photoelectric aesthetic procedures.